Descripción
Whole-genome shotgun metagenomic sequencing of the human gut microbiome from a single stool sample. It characterises ~2,008 species (bacteria, archaea, fungi, parasites and DNA viruses), the full resistome (CARD, 4,500+ genes), virulence factors and toxins (VFDB) and the functional profile (HUMAnN3) — all from the same DNA, in one assay.
Includes:
- Sample collection kit (DNA/RNA Shield tube + spatula + prepaid envelope; shipping to the laboratory included)
- DNA extraction and quality control
- Shotgun PE150 sequencing (≥20 M reads, ~6 Gb per sample) with human-read depletion (GRCh38)
- Full bioinformatics: Kraken2/Bracken + MetaPhlAn4 + HUMAnN3 + AMRFinderPlus + CARD + VFDB
- 8 clinical indices: GMHI, GMWI2, DI V2, EDS, Butyrate Capacity, CRC Risk, IBD (CD/UC) and C. difficile Risk
- Severity triage (HIGH / MODERATE / INFORMATIONAL) and pharmacological confounder detection (PPI, metformin, mesalazine, oral iron)
- Antimicrobial stewardship aligned with EUCAST 2025 / IDSA / SEIMC
- Clinical PDF report (14 sections) signed by a licensed health biologist
Turnaround:
Up to 30 days from receipt of the sample at the laboratory.
Sample:
Fresh stool (2-5 g) in a DNA/RNA Shield stabilisation tube (kit included). No fasting required. Stable at room temperature for up to 30 days.
Clinical decision-support tool; it is not a medical diagnosis on its own. Detection of resistance genes does not equal phenotypic resistance (EUCAST 2025).
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